Back
Home » Health
  •  
    Filmi Bollywood
    • Family Of Thakurganj Movie Review: Visit This Family At Your Own Risk!
    • Jhootha Kahin Ka Movie Review: It Takes Its Title Too Seriously & Fails To Deliver Laughs!
    • GOOD NEWS! Arjun Rampal & Gabriella Demetriades Blessed With A Baby Boy
    • Happy Birthday Priyanka Chopra: Alia Bhatt & Anil Kapoor Have The Sweetest Wishes For Our Desi Girl
    • Mission Mangal Trailer Out: Goosebumps Assured
    • Nora Fatehi REACTS To Koena Mitra Calling 'Saki Saki' Remake A MESS!
    • Rajesh Khanna's Death Anniversary: Netizens Remember The First Superstar Of Bollywood
    • Akshay Kumar To Donate Rs 2 Crore Towards Relief Work In Assam, Kaziranga National Park
    • WAIT WHAT! Sidharth Malhotra Failed Class 9 Because Of This SHOCKING Reason
    • Dharmendra APOLOGIZES To Wife Hema Malini After Trolling Her: 'Humka Maafi De Diyo'
    • Salman Khan To Launch & Romance Mahesh Manjrekar's Daughter In Dabangg 3
    • Happy Birthday Priyanka Chopra: These Quotes Speak Volumes About Her Love For Nick Jonas!
    • Veteran Bengali Actor Swarup Dutta Passes Away Due To Cardiac Arrest In Kolkata
    • Priyanka Chopra-Nick Jonas Are Made For Each Other & These Pictures Are Proof!
    • REVEALED! This Is How Bhumi Pednekar Plans To Celebrate Her 30th Birthday
    • New Troubles Crop Up For Prabhas! Saaho Gets DELAYED Yet Again Owing To These Reasons...
    • That One Gesture Of Nick Jonas That Changed His & Priyanka Chopra's Lives Forever!
    • Rishi Kapoor Opens Up About His Battle With Cancer: 'It's Been A Difficult Time'
    • Priyanka Chopra On Sophie Turner's 'Game Of Thrones' Emmy Nomination: 'Incredibly Proud Of You'
    • Varun Dhawan, Arjun Kapoor & Others Tried The FaceApp Old Filter & The Results Were HILARIOUS!
Granuloma Inguinale (Donovanosis): Symptoms, Stages, Causes & Treatment
Boldsky | 17th Apr, 2019 03:55 PM

Granuloma inguinale is a genital ulcerative disease caused by the bacterium Klebsiella granulomatis. That is, Granuloma inguinale is a sexually transmitted infection (STI). Also known as donovanosis, the infection causes lesions in the genital and anal regions . The STI is characterised by pain-free genital ulcers that look like the pox. The infection is mostly found in sub-tropical and tropical regions and is rarely reported in developed countries. In some of the developing countries, such as India, Papua New Guinea, and the Caribbean, the infection is regarded as an endemic , .

The bacterium Klebsiella granulomatis infects the skin around the genitals and causes ulcers which result in the destruction of the skin around the affected area. This destructive nature of the infection elevates the risk of getting affected by other pathogenic microbes.

Granuloma inguinale is infectious, that is, it can spread from one person to other . It is mostly spread through the means of vaginal or anal intercourse and rare cases of infection through oral sex have been reported. However, anal intercourse is suspected to be the most frequent source of infection. About 50 per cent of the affected (men and women) have developed lesions in the anal region .

Studies have revealed that men are most likely to be affected by the infection than women and commonly occurs in people aged between 20 to 40. Most of the cases of the STI reported are in people who have travelled to places that are at a high risk of the infection . And, a very small proportion of people may be infected through direct, non-sexual contact (skin to skin).

Symptoms Of Granuloma Inguinale

The common signs indicating the development of the infection are small, painless nodules (pimple like) which develops into an open and fleshy lesion. The infection develops in the genital area and in some cases, mouth sores can also develop. This aggravates until the infected tissue gets mutilated and the infection will continue to latch onto other tissues , .

Apart from this, the symptoms of the sexually transmitted disease can be described in line with the stages of Granuloma inguinale.

Stages Of Granuloma Inguinale

The signs of the infection develop at a slow pace. That is, once the individual comes in contact with the bacteria it will take 7 to 10 days to experience the symptoms. Within a period of 12 weeks, the symptoms will be at their maximum capacity .

  • Stage one: In the initial stage, the small nodule will spread to the surrounding tissue. The affected tissues will be lost and the area will turn pink (or a very light red). The small bumps found around the anus and genitals turn into raised red nodules with a velvety texture. The nodules will be painless, however, injuring them can cause bleeding.
  • Stage two: By now, the bacteria will begin to destroy the skin and cause shallow ulcers that will spread from the genitals and anus to the thighs and lower abdomen. The ulcers may have a foul smell and will be lined with granulated tissue.
  • Stage three: Upon reaching the third stage, the infection will become deep and the ulcers will turn into morph tissue.
Causes Of Granuloma Inguinale

The infection is caused by the Klebsiella granulomatis bacteria. One can contract the infection by having vaginal or anal intercourse with an infected partner. In very rare cases, it has spread through oral sex. Apart from these, it can spread from a mother to a child during delivery .

Complications Of Granuloma Inguinale
  • Loss of skin colour in the genital area
  • Genital damage and scarring
  • Permanent genital swelling due to scarring
  • Cancer in the sore
  • Narrowing of the vagina, anus or urethra
  • Damage to the bones or bowel, if the bacteria spread through the blood to other sites

It is often difficult to diagnose the infection in its early stage due to the slow development of the ulcers.

If the ulcers do not heal after a month, your doctor will advise a skin biopsy of the lesions called the punch biopsy. Under this one, the doctor will remove a small area of the ulcer with a circular blade and will be tested for the presence of Klebsiella granulomatis bacteria . In some cases, scrapings of the lesions are used to detect the presence of the bacteria.

The diagnosis will also include blood tests to check the presence of other sexually transmitted diseases , .

Treatment For Granuloma Inguinale

Antibiotics such as azithromycin, doxycycline, ciprofloxacin, erythromycin, and trimethoprim-sulfamethoxazole are used. The antibiotics will be used for a long period of time, until the sores are completely healed, and depending on the length of time since infection and the stage of infection. Most of the antibiotics are prescribed for a period of three weeks, however, some may take more time to heal the ulcer .

If the ulcers are painful, the doctor will advise for painkillers .

A follow-up examination is essential, as the sexually transmitted infection can reappear even if the lesions have gone down completely .

Prevention Of Granuloma Inguinale
  • Using condoms for vaginal and anal sex significantly reduces the risk of the infection and sexually transmitted diseases .
  • Avoid sex with individuals who have a visible genital ulcer or sore.
  • Before travelling to a developing country, run a thorough check on the diseases that are prevalent there, and adopt suitable preventive measures .
   
 
Health and Life
  • Top 15 Health Benefits of Quail Eggs
  • Did You Know That Exposure To Pesticides Can Lead To Depression?
  • Shravan Month 2019: What Foods To Eat And What Foods To Avoid
    • Cysts: Causes, Types, Symptoms & Treatment
    • Black Eye: Causes, Symptoms, Diagnosis & Treatment
    • What Is Horned Melon? Its Benefits, Side Effects And Recipe
      • What Are Navy Beans? Their Benefits, Side Effects And Recipe
      • Kunal Khemu's Fitness And Diet Tips
      • Diet For Jaundice: Foods To Eat And Foods To Avoid
        • Multiple Sclerosis: Causes, Symptoms, Diagnosis And Treatment
        • 7 Nutritious Foods That Help Promote Beard Growth
        • Epidermodysplasia Verruciformis (EV): Causes, Symptoms, Diagnosis And Treatment
          • 20 Healthy Snacks To Curb Hunger
          • Sustainable Menstruation Through Menstrual Cup: Keeping You & The Earth Clean
          • What Is Solomon's Seal? Its Benefits, Side Effects And Recipes
            • 8 Amazing Health Benefits Of Rose Hip
            • Anand Kumar Of Super 30 Reveals He Has Acoustic Neuroma - All You Need To Know About This Condition
            • 6 Amazing Benefits Of Ice Cubes For Your Health
              • 7 Fascinating Health Benefits Of Chicory You Must Know!
              • Empty Nose Syndrome: Causes, Symptoms, Diagnosis & Treatment
              • How Diabetes Affects Male Fertility